Lymphomatoid papulosis (LyP) with 6p25.3 rearrangement

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CD8+ Lymphomatoid Papulosis.

Lymphomatoid papulosis (LyP) is defined as a histologically malignant, but clinically benign condition. It can appear as erythematous pink to purple papules or nodules. Immunophenotyping studies of the lymphomatoid papulosis lesions have shown a predominance of a CD4 expression and negativity for CD8. However, a positive CD8 expression has rarely been reported for LyP. Herein we report on a cas...

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A child with mastocytosis and lymphomatoid papulosis

A change in clinical behavior of a disease should prompt search for differential diagnoses. Here, the appearance of ulcerated skin nodules in a preexisting cutaneous mastocytosis revealed a concurrent lymphomatoid papulosis - a CD30+ lymphoproliferative skin disease with histological features of a malignant lymphoma, but with a benign self-healing course.

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Lymphomatoid Papulosis –3 Case Reports

We present two cases of childhood and one case of adult Lymphomatoid papulosis (LyP), an entity which is commonly misdiagnosed and poorly described in the paediatric dermatology literature. Clinically and histologically, the features of LyP in children can mimic insect bite reaction, with prominent dermal neutrophils and eosinophils. However, CD30 immunohistochemical staining of atypical lympho...

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[Oral involvement in lymphomatoid papulosis].

Lymphomatoid papulosis is a cutaneous lymphoma with an indolent clinical behaviour characterized by chronic development of recurrent, self-limited lesions appearing as necrotic papules and with a pathology compatible with T cell lymphoma. Mucosal involvement by lymphomatoid papulosis is very rare but has been reported in the literature. It usually appears as ulcers in patients previously diagno...

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Immuno Pathogenesis of Pregnancy induced Lymphomatoid Papulosis

We present the immuno pathogenesis of Lymphomatoid Papulosis associated with mild immuno suppression. The foundation of our observation was based on case reports discussing the development of LyP while concurrently using immune modulators. The medically altered immune state is mirrored by the hormone-induced changes of pregnancy. Furthermore, we explain how the natural progression of pregnancy ...

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2014

ISSN: 1768-3262

DOI: 10.4267/2042/53488